What is non-allelic gene interaction

Difference between epistatic and hypostatic gene.

The Main difference between epistatic gene and hypostatic gene that is The epistatic gene is a gene that affects the expression of another gene in a different location, while the hypostatic gene is the gene that is subject to interference from the epistatic gene.

Certain genes depend on other non-allelic genes for their expression. Epistasis is a form of gene interaction in which one gene disrupts or masks the expression of another gene in a different location. Hence, it's a kind of non-allelic gene interaction. In this particular gene interaction, two genes interact and they are the epistatic gene and the hypostatic gene. Accordingly, the gene that masks the expression of another gene is known as the epistatic gene, while the gene whose expression is affected is known as the hypostatic gene is.

1. Overview and main difference
2. What is an epistatic gene?
3. What is a hypostatic gene?
4. Similarities between epistatic gene and hypostatic gene.
5. Side by side comparison - epistatic gene versus hypostatic gene in tabular form
6. Summary

What is an epistatic gene?

Epistasis is a gene interaction that can affect the phenotype of a particular gene. In this particular gene interaction, one gene suppresses the expression of another gene that is in a different location. Hence, the epistatic gene refers to the gene that disrupts or masks the phenotype of the second gene.

For example, the total baldness gene is epistatic to the brown hair gene. Therefore, the epistatic gene can alter the expression of the phenotype of the other gene.

What is a hypostatic gene?

The hypostatic gene is the gene whose expression in an epistatic event is influenced by the epistatic gene. The phenotype of the hypostatic gene changes due to the influence of the epistatic gene. Therefore, the expression of the hypostatic gene depends entirely on the epistatic gene. More often, the epistatic gene suppresses the expression of the phenotype of the hypostatic gene.

For example the alleles that determine the color of the dog; Labrador Retrievers that are black or brown are alleles of the hypostatic gene, while the color of the chocolate shell is the expression of the epistatic gene of it.

What are the Similarities Between Epistatic Gene and Hypostatic Gene?

  • Epistatic gene and hypostatic gene are two types of genes that are involved in an epistatic event.
  • The epistatic gene affects the phenotype of the hypostatic gene.
  • Both epistatic and hypostatic genes are also involved in the non-allelic gene interaction.

What is the difference between epistatic and hypostatic gene?

The epistatic gene can suppress or mask the phenotype of another gene in a different location. On the other hand, the gene whose expression is impaired is called a hypostatic gene. Hence, this is the main difference between the epistatic gene and the hypostatic gene.

In addition, the epistatic gene can inhibit, suppress or mask the phenotype of the hypostatic gene. In Labrador Retriever, the color of the chocolate coat is a result of an epistasis event. However, the brown or black coat colors are the allele expressions of the hypostatic gene.

The following is a table of the difference between the epistatic gene and the hypostatic gene.

Summary - epistatic gene versus hypostatic gene.

Epistasis is a type of non-allelic gene interaction. Hence, it occurs in different locations between genes. An allele of one gene suppresses or masks the visual output or phenotype of another gene. This epistatic event occurs between two genes, namely the epistatic gene and the hypostatic gene. Summary of the difference between epistatic and hypostatic gene; The epistatic gene is the gene that suppresses or masks the second gene in a different location, while the hypostatic gene is the gene whose phenotype is affected by the epistatic gene. In simple terms, the epistatic gene affects the expression of the hypostatic gene in that particular gene interaction.