How many days would paracetamol tablets expire

Mexalen 500mg tablets

Prescription required:No
Active ingredient:500 mg paracetamol
Marketing authorization holderRATIOPHARM ARZNEIMITTEL GMBH, VIENNA
Application:Aniline derivatives (monopreparations)

How does the remedy work?

The active ingredient paracetamol primarily has an analgesic and fever lowering effect. This effect arises from the inhibition of the production of prostaglandins (messenger substances). In contrast to other painkillers such as non-steroidal anti-inflammatory drugs (NSAIDs), Mexalen has only a weak anti-inflammatory effect, but is better tolerated by the stomach. Paracetamol is broken down in the liver and excreted mainly in the urine.

In which areas of application is the product used?

how do you apply the product?

  • Mexalen 500mg tablets are taken with some liquid.
  • There should be at least six hours between two ingestions.
  • Adults and adolescents from twelve years of age (from 43 kg body weight): One tablet (500 mg) up to four times a day
  • The maximum daily dose is 2000 mg (4 tablets).
  • Children between the ages of six and twelve can take half a tablet three times a day.
  • Mexalen is available in other forms of administration for younger children.
  • In people with impaired liver function (e.g. Gilbert syndrome - congenital liver disease), the dose must be reduced or the interval between two doses increased.
  • In people with impaired kidney function, the interval between two doses must be at least eight hours.
  • If you forget a dose, take the normal dose the next time you take it, not a double dose.

When should the product not be used?

  • if you are hypersensitive to paracetamol or another component of Mexalen 500mg tablets
  • with severely reduced liver function
  • if there is a genetic deficiency in glucose-6-phosphate dehydrogenase
  • with alcoholism
  • Children under 6 years

Can the product be used by pregnant and breastfeeding women?

There is no evidence of a harmful effect of paracetamol during pregnancy or breastfeeding. Nevertheless, a possible intake should only take place after a careful risk-benefit assessment, with a low dose, limited to single doses and after consultation with a doctor.

Which side effects can occur?

Side effects rarely occur. In addition to other side effects, allergic skin reactions such as reddening or nettles, possibly with a rise in temperature and damage to the mucous membrane, may occur. Blood formation disorders in the bone marrow are very rare. If poisoning from an overdose can result in kidney and severe liver damage.

Interactions are known with the following substances:

  • Anti-epileptic drugs (anti-epileptic drugs)
  • Rifampicin (anti-tuberculosis drug)
  • Chloramphenicol (a type of antibiotic)
  • Salicylamides (certain pain relievers)
  • Anticoagulants (blood coagulants, e.g. Marcoumar)
  • Metoclopramide and cisapride (drugs that make gastric emptying faster)
  • Probenecid (anti-gout medicine)
  • Zidovudine (anti-HIV medicine)
  • Nizatidine (anti-stomach acid agent)
  • Propantheline (used to slow down gastric emptying)
  • Lamotrigine (a medicine used for epilepsy and major depression)
  • Cholestyramine (a medicine used to lower blood lipids)
  • alcohol

Warning notices

  • Do not drink alcohol while taking Mexalen 500mg tablets.
  • If alcohol is consumed while taking Mexalen 500mg tablets, the risk of liver damage is high.
  • In the case of liver dysfunction or severe kidney damage, it may be necessary to select a lower dose or to resort to another drug.
  • Taking too high doses and taking them for several months can lead to severe liver and kidney damage.
  • Long-term treatment with a high dose of painkillers can lead to headaches that should not be treated with higher doses.
  • Caution is also advised with: long-lasting (chronic) undernourishment or malnutrition and with certain urinary stones (oxalate stones)
  • If you take too many Mexalen 500mg tablets, contact a doctor. Serious damage to the liver and kidneys can result from an overdose. An overdose leads to symptoms such as nausea, vomiting, abdominal pain and paleness. Children, the elderly and people with liver and kidney diseases are more likely to suffer from Mexalen poisoning.
  • If you abuse Mexalen 500mg tablets over a long period of time in high doses and suddenly stop taking them, dizziness, nervousness and pain may occur. Nevertheless, do not take Mexalen 500mg tablets any more, but seek advice from a doctor.
  • If the fever or pain does not go away despite taking Mexalen 500mg tablets, consult a doctor after three days at the latest.
  • In laboratory tests, taking Mexalen 500mg tablets can falsify the results of blood sugar and uric acid determination.

Note: The list of drugs does not in any way represent a recommendation, sales promotion or advertising of the individual drugs in any way.

The information is by no means conclusive and is not a substitute for medical or other specialist advice.

In particular with regard to side effects, contraindications and other information, the attending doctor or pharmacist should be consulted.



Status of information: July 2019